Your research question is what you are looking to answer with your research, whether that be a topic paper, experiment, or another form of research.
Keep these in mind:
Who? Who is the specific person/group to which you would like to limit your research?
What? What specific aspect of the broad topic idea is interesting to you?
Where? To which specific geographic area or region would you like to limit your research?
When? On what time period would you like your research focused?
Why? Why do you think this is an important/interesting topic?
Make sure your question can't be answered with just a yes or no or with a statistic. You need to be able to make an argument or take a stance. An easy way to do this is by asking why or why not?
Tips for Clinical Questions
If you are trying to define a good clinical foreground for a research question try using PICO!
Population/Patient/Problem -> "Among family-members of patients with early-onset dementia"
Intervention (cause/prognosis) -> "does listening to tranquil music"
Comparison (optional) -> "as opposed to not listening to tranquil music"
Outcome -> "make a difference in the reduction of reported anxiety?"